*N* | number of labs | 100 |

*b* | base rate of true hypotheses | 0.1 |

*r*_{0} | initial replication rate for all labs | {0, 0.01, 0.2, 0.5} |

*e*_{0} | initial effort for all labs | 75 |

*w*_{0} | initial power for all labs | 0.8 |

*η* | influence of effort on productivity | 0.2 |

*c*_{R+} | probability of publishing positive replication | 1 |

*c*_{R−} | probability of publishing negative replication | 1 |

*V*_{N} | pay-off for publishing novel result | 1 |

*V*_{R+} | pay-off for publishing positive replication | 0.5 |

*V*_{R−} | pay-off for publishing negative replication | 0.5 |

*V*_{O+} | pay-off for having novel result replicated | 0.1 |

*V*_{O−} | pay-off for having novel result fail to replicate | −100 |

*d* | number of labs sampled for death and birth events | 10 |

*μ*_{r} | probability of *r* mutation | {0, 0.01} |

*μ*_{e} | probability of *e* mutation | {0, 0.01} |

*μ*_{w} | probability of *w* mutation | {0, 0.01} |

*σ*_{r} | standard deviation of *r* mutation magnitude | 0.01 |

*σ*_{e} | standard deviation of *e* mutation magnitude | 1 |

*σ*_{w} | standard deviation of *w* mutation magnitude | 0.01 |